By Nneka Nwogwugwu
A South African biotech firm Afrigen said on Thursday that it has produced the first mRNA COVID vaccine made on the continent and that it will be ready for clinical trials in November.
Cape Town-based Afrigen Biologics and Vaccines is leading the pilot project, backed by the World Health Organization (WHO) and the COVAX initiative, to tweak Moderna’s shot.
“At laboratory scale we have a vaccine that we now need to test,” Afrigen’s managing director Petro Terblanche, told AFP, adding the first shot was ready during the second week of January.
Tests on animals will start next month, “but the human studies will only start around November 2022,” she said after meeting a group of officials sponsoring the project.
Afrigen researchers sequenced the publicly available genetic code that Moderna used to make their vaccine, made the DNA, the RNA and produced their own shot.
“So we have completed the process from the design to a final formulation, but it’s small scale, but it’s a good start, it’s fabulous start,” said the laboratory’s chief.
She spoke after the UN-backed global Medicines Patent Pool gave the firm a 39-million-euro ($45 million) grant.
Their mRNA vaccine can be kept at warmer temperatures, making them easier to store in low- and middle-income settings. The original jab requires expensive -250C to -150C refrigeration.
Charles Gore, MPP’s executive director said in a statement that his organisation was “delighted to support Afrigen and its African partners to greatly expand local manufacturing capacity and reduce today’s gross inequity”.
The grant will cover the technology transfer hub’s work for five years, through 2026.
Source: Gulf news
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